Optimize Pseudomonas Aeruginosa Treatment with the MolecuLight i:X

MolecuLight Case Study - Practitioner's Bio Icon

Practitioner's Bio
Rose Raizman, RN-EC, MSc, with over 19 years of experience, leads the Save Our Skin (SOS) team at Scarborough & Rouge Hospital located in Toronto, Canada, to combat pressure ulcers of hospital inpatients. She also oversees the wound care clinic for inpatients and outpatients.

“I suspected colonization, and
MolecuLight i:X guided me to
efficiently target debridement and
topical therapy application to ensure
maximum removal of the bacterial
load and prevent further

- Rose Raizman, RN-EC, MSc

Clinical Synopsis: Clinician used MolecuLight i:X to confirm the presence and location of Pseudomonas aeruginosa in a venous leg ulcer. As seen in Figure 3, the white/cyan color suggests heavy levels of Pseudomonas aeruginosa pre-debridement (the white/cyan color is due to signal oversaturation), which would otherwise be invisible to the unaided eye. The clinician uses this information to guide debridement of bioburdened tissue and re-imaged the wound post-debridement. Figure 4 indicates a reduction in bioburden post-debridement, but not the eradication of Pseudomonas aeruginosa.

Figure 1: Standard Imaging ModeTM Venous leg ulcer pre-debridement.

Figure 2: Standard Imaging ModeTM Venous leg ulcer post-debridement.

Figure 3: Fluorescence Imaging ModeTM Venous leg ulcer pre-debridement. White/cyan regions suggest heavy levels of Pseudomonas aeruginosa.

Figure 4: Fluorescence Imaging ModeTM Venous leg ulcer post-debridement. Less white observed, cyan fluorescence suggests Pseudomonas aeruginosa.

Patient Condition:

Wound Etiology and Location • Venous leg ulcer, left-leg
Patient Demographics • Female, 78 years old
Patient-Related Challenges • Home care nurses had stopped using prescribed antimicrobial against clinician orders
Patient General Care Paradigm • Antimicrobial paste
• Local wound care
Clinician Stated Utility of the MolecuLight i:X • Visualization of periwound bacteria led to larger cut dressings
• Guided selection of antimicrobial (silver) cream and dressings

Conclusion: The MolecuLight i:X images (Figure 4) provided important evidence that Pseudomonas aeruginosa was still present after debridement, which helped the clinician make the decision at the point of care to select antimicrobial (silver) cream and dressings as well as applying a larger dressing to fully manage the remaining bacterial load. This example shows how the MolecuLight i:X may provide important insights about the location of bacteria so clinicians can target debridement and treat wounds more effectively, compared to the standard of care